Saypha®

Saypha® – Monophasic hyaluronic acid fillers from Croma for natural volume and comfort
Saypha® is a series of HA fillers from Croma Pharma with non-animal hyaluronic acid, developed for aesthetic injection with a focus on volume, correction of folds, improved skin structure and patient comfort. The products are available with or without lidocaine and are CE-marked (typically CE0123) with high standards of quality and safety.


Advantages of Saypha®
High HA content (usually about 23 mg/ml) for good volume and hold.
Products with lidocaine for increased comfort during injection.
Manufactured with BDDE crosslinking (low levels) for stability and safety.
Available variants for different treatment needs, from fine lines to deeper volume restoration.

Areas of application
Saypha® products are used for:

Correction of nasolabial folds, marionette lines and superficial to medium-deep wrinkles.
Volume restoration in cheeks, chin and facial contour.
Lip contour and volume augmentation with Filler and Filler Lidocaine variants.
Superficial lines and moisture booster effect with Saypha RICH, for thin or worn skin.

Technology & formulation
Hyaluronic acid of non-animal origin, which reduces immunological risk.
BDDE cross-linking with a concentration of ≤ 2 ppm.
Variants with 0.3% lidocaine for pain reduction during injection.
Monophasic and viscoelastic gels with properties that balance elasticity and durability for varying injection depths.

Treatment & durability
Injection with needle or cannula; usually mid- to deep dermis depending on the product.
Results are visible immediately; maximum effect develops in the following weeks.
Some redness or swelling may occur but usually subsides quickly.
Durability depends on the product variant and treated area, often 6-12 months.

Saypha® offers practitioners a complete range for filling, volume, definition and skin enhancement – with a focus on naturalness, safety and comfort.